KAZN-AS1

Across TCGA pan-cancer cohorts, KAZN-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated KAZN-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher KAZN-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KAZN-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and ESCA show a favorable association.

KICH, ACC, and LGG are the cancer types where KAZN-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.253	0.921	<.001	108	view →
ACC	OS	Tertile	All	0.185	0.821	<.001	66	view →
LGG	DFS	Tertile	All	0.505	0.758	<.001	36	view →
BRCA	OS	Quartile	II,III,IV	0.931	0.968	.007	31	view →
LUAD	DFS	Tertile	III,IV	0.460	0.682	.033	27	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	27	view →
UCEC	DFS	Tertile	III,IV	0.744	0.812	.030	24	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
CESC	DFS	Tertile	III,IV	0.920	0.648	.022	18	view →
TGCT	DFS	Tertile	II,III,IV	0.621	0.949	.034	18	view →
ESCA	DFS	Quartile	III,IV	0.647	0.364	.011	18	view →
PAAD	DFS	Tertile	All	0.182	0.492	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

KAZN-AS1–KICH (OS)

Open the KICH breakdown →