KAZALD1

Across TCGA patient cohorts, KAZALD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KAZALD1-associated genes across cancer lineages are GTPBP10, PLEKHA8, and GAB1. Each is linked with KAZALD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KAZALD1-to-partner and partner-to-KAZALD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAZALD1 versus GTPBP10 in UCEC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAZALD1→partner) and Y-score (partner→KAZALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GTPBP10 →	-0.549	-0.768	<.001	.004	3	1
UCEC	PLEKHA8 →	-0.813	-1.272	.006	.002	3	1
UCEC	GAB1 →	-0.636	-1.017	.009	.008	3	1
UCEC	PCDHB7 →	-1.112	-0.683	.008	.005	3	1
UCEC	PCDHB15 →	-1.180	-0.749	<.001	.002	3	1
UCEC	PCDHB8 →	-2.110	-0.869	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,284 associations by consensus.

KAZALD1 vs GTPBP10 — UCEC

Explore this scatter interactively →