KATNIP

Across TCGA cell cohorts, KATNIP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,339 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KATNIP-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Negative regulation of autophagy, and Cytosolic transport. Each is linked with KATNIP in more than 18 cancer types. Because this analysis shows association rather than direction, both KATNIP-to-partner and partner-to-KATNIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagosome maturation grouped by KATNIP-low versus KATNIP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNIP→partner) and Y-score (partner→KATNIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of autophagosome maturation →	+0.126	+0.756	<.001	<.001	3	19
STOMACH	Negative regulation of autophagy →	+0.110	+1.292	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.080	+1.029	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.082	+1.120	<.001	<.001	3	18
OVARY	Negative regulation of organelle assembly →	+0.065	+0.740	.001	<.001	3	17
STOMACH	Cellular response to starvation →	+0.066	+1.119	.003	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

Negative regulation of autophagosome maturation by KATNIP expression — LUNG_SCLC

Explore this box plot interactively →