KATNBL1

Across TCGA patient cohorts, KATNBL1 mutation is significantly associated with the RNA expression of many other genes, with 2,530 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KATNBL1-associated genes across cancer lineages are EIF4EBP2P3, RPS12P15, and VN1R105P. Each is linked with KATNBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KATNBL1-to-partner and partner-to-KATNBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF4EBP2P3 grouped by KATNBL1-low versus KATNBL1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNBL1→partner) and Y-score (partner→KATNBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	EIF4EBP2P3 →	+0.096	+5.624	<.001	.002	3	2
COAD	RPS12P15 →	+0.148	+4.693	<.001	.007	3	2
COAD	VN1R105P →	+0.064	+5.251	<.001	.003	3	2
BRCA	TRDD1 →	+1.367	+9.057	<.001	.003	3	2
UCEC	YTHDF3-AS1 →	+0.707	+1.928	<.001	.001	3	1
UCEC	ATP2B1-AS1 →	-0.282	-1.820	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,530 associations by consensus.

EIF4EBP2P3 by KATNBL1 expression — SKCM

Explore this box plot interactively →