KATNAL1

Across TCGA pan-cancer cohorts, KATNAL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KATNAL1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher KATNAL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KATNAL1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

LSCC, CCRCC, and GBM are the cancer types where KATNAL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.662	0.920	.009	20	view →
CCRCC	OS	Median	III,IV	0.573	0.825	.028	13	view →
GBM	DFS	Tertile	All	0.872	0.631	.001	11	view →
PDAC	DFS	Quartile	II,III,IV	0.632	0.892	.015	7	view →
LUAD	OS	Median	III,IV	0.411	0.808	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KATNAL1–LSCC (OS)

Open the LSCC breakdown →