KATNAL1

Across TCGA patient cohorts, KATNAL1 mutation is significantly associated with the RNA expression of many other genes, with 2,488 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KATNAL1-associated genes across cancer lineages are C9orf152, IGHD3-16, and RAD51AP2. Each is linked with KATNAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KATNAL1-to-partner and partner-to-KATNAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf152 grouped by KATNAL1-low versus KATNAL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNAL1→partner) and Y-score (partner→KATNAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C9orf152 →	+1.023	+2.392	.004	<.001	3	2
UCEC	IGHD3-16 →	+1.049	+2.211	<.001	<.001	3	2
UCEC	RAD51AP2 →	+0.131	+1.924	.006	.005	3	2
UCEC	IGHD4-17 →	+0.674	+2.299	<.001	.004	3	2
UCEC	RNA5SP417 →	+0.457	+1.989	<.001	.004	3	2
LUAD	RNA5SP109 →	+0.447	+6.197	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,488 associations by consensus.

C9orf152 by KATNAL1 expression — UCEC

Explore this box plot interactively →