KATNAL1

Across TCGA cell cohorts, KATNAL1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KATNAL1-associated genes across cancer lineages are HCRTR2, OR13C3, and RFPL3. Each is linked with KATNAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KATNAL1-to-partner and partner-to-KATNAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HCRTR2 grouped by KATNAL1-low versus KATNAL1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNAL1→partner) and Y-score (partner→KATNAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HCRTR2 →	+0.018	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR13C3 →	+0.030	+4.874	<.001	.002	3	1
LARGE_INTESTINE	RFPL3 →	+0.032	+2.925	.001	.007	3	1
LARGE_INTESTINE	HMX3 →	+0.710	+3.531	<.001	.007	3	1
LARGE_INTESTINE	FMO3 →	+0.410	+3.963	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

HCRTR2 by KATNAL1 expression — BLOOD_Leukemia

Explore this box plot interactively →