Across TCGA pan-cancer cohorts, KATNA1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KATNA1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher KATNA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KATNA1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

LSCC, UCEC, and HNSC are the cancer types where KATNA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.993	0.878	.004	33	view →
UCEC	OS	Median	III,IV	1.000	0.449	.010	26	view →
HNSC	DFS	Tertile	All	1.000	0.915	.011	10	view →
LUAD	OS	Median	III,IV	0.229	0.717	.010	4	view →
CCRCC	DFS	Tertile	II,III,IV	1.000	0.853	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: KATNA1 tumor-vs-normal RNA expression · all KATNA1 data types