KATNA1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KATNA1 mutation is significantly associated with the RNA expression of many other genes, with 1,037 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KATNA1-associated genes across cancer lineages are LINC00474, RNA5SP229, and RN7SL418P. Each is linked with KATNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KATNA1-to-partner and partner-to-KATNA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNA1→partner) and Y-score (partner→KATNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCLINC00474 →+0.102+5.015<.001.00932
HNSCRNA5SP229 →+0.537+5.069<.001.00832
HNSCRN7SL418P →+0.163+5.736<.001.00332
HNSCRNA5SP422 →+1.128+6.468<.001.00132
UCECHMX3 →+0.509+1.827.002.00632
UCECRNU6-218P →+0.498+1.831<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,037 associations by consensus.

Exploration