Across TCGA patient cohorts, KATNA1 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KATNA1-associated genes across cancer lineages are FoxM1, INPP4B, and JNK_pT183_Y185. Each is linked with KATNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KATNA1-to-partner and partner-to-KATNA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNA1→partner) and Y-score (partner→KATNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.229	+2.415	.027	.003	3	1
UCEC	INPP4B →	-0.289	-3.321	.026	.009	3	1
UCEC	JNK_pT183_Y185 →	-0.164	-3.459	.015	.005	3	1
UCEC	JNK2 →	+0.195	+3.087	.014	<.001	3	1
UCEC	Ku80 →	+0.273	+1.920	.004	.009	3	1
UCEC	p38-MAPK →	-0.134	-2.301	.043	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

KATNA1 survival (RNA) · tumor vs normal (RNA) · all KATNA1 data types