Across TCGA cell cohorts, KATNA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,867 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KATNA1-associated GO terms across cancer lineages are Negative regulation of ubiquitin protein ligase activity, Regulation of mitotic sister chromatid separation, and Regulation of chromosome separation. Each is linked with KATNA1 in more than 18 cancer types. Because this analysis shows association rather than direction, both KATNA1-to-partner and partner-to-KATNA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNA1→partner) and Y-score (partner→KATNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of ubiquitin protein ligase activity →	+0.239	+0.876	<.001	.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.137	+0.835	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome separation →	+0.139	+0.922	<.001	<.001	3	17
BREAST	Regulation of chromosome segregation →	+0.127	+0.811	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.116	+0.806	<.001	<.001	3	17
KIDNEY	Regulation of mitotic sister chromatid segregation →	+0.131	+0.811	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,867 associations by consensus.

Exploration

KATNA1 survival (RNA) · tumor vs normal (RNA) · all KATNA1 data types