Across TCGA cell cohorts, KATNA1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KATNA1-associated genes across cancer lineages are C6orf118, UTF1, and OR4A47. Each is linked with KATNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KATNA1-to-partner and partner-to-KATNA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KATNA1→partner) and Y-score (partner→KATNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.175	+3.793	<.001	.007	3	1
LARGE_INTESTINE	UTF1 →	+0.022	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR4A47 →	+0.018	+4.437	<.001	.004	3	1
LARGE_INTESTINE	INSRR →	+0.030	+4.584	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

KATNA1 survival (RNA) · tumor vs normal (RNA) · all KATNA1 data types