KAT8

Across TCGA cell cohorts, KAT8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,798 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KAT8-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cell PML body, Positive regulation of macrophage proliferation, and Regulation of chromatin organization. Each is linked with KAT8 in more than 15 cancer types. Because this analysis shows association rather than direction, both KAT8-to-partner and partner-to-KAT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cell PML body grouped by KAT8-low versus KAT8-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT8→partner) and Y-score (partner→KAT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Symbiont-mediated disruption of host cell PML body →	+0.113	+0.870	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of macrophage proliferation →	+0.178	+0.719	.006	.002	3	14
BONE	Regulation of chromatin organization →	+0.145	+0.875	<.001	<.001	3	14
LUNG_SCLC	Regulation of ATPase-coupled calcium transmembrane transporter activity →	-0.237	-0.684	.001	<.001	3	14
STOMACH	Regulation of myoblast fusion →	+0.102	+0.564	<.001	<.001	3	13
BONE	Regulation of nucleotide-excision repair →	+0.139	+0.755	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,798 associations by consensus.

Symbiont-mediated disruption of host cell PML body by KAT8 expression — LIVER

Explore this box plot interactively →