KAT7

Across TCGA pan-cancer cohorts, KAT7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KAT7 data layer compared with 28 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KAT7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KAT7 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

HNSC, CCRCC, and LSCC are the cancer types where KAT7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.597	0.848	.002	39	view →
CCRCC	DFS	Tertile	II,III,IV	0.780	0.430	.004	31	view →
LSCC	OS	Median	All	0.920	0.733	.002	15	view →
LUAD	OS	Tertile	II,III,IV	0.872	0.276	.007	8	view →
GBM	OS	Tertile	All	0.508	0.301	.031	3	view →
PDAC	OS	Tertile	II,III,IV	0.316	0.500	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KAT7–HNSC (OS)

Open the HNSC breakdown →