KAT7

Across TCGA cell cohorts, KAT7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,438 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KAT7-associated GO terms across cancer lineages are Positive regulation of hematopoietic stem cell proliferation, DNA replication-dependent chromatin disassembly, and Regulation of DNA-templated DNA replication initiation. Each is linked with KAT7 in more than 19 cancer types. Because this analysis shows association rather than direction, both KAT7-to-partner and partner-to-KAT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of hematopoietic stem cell proliferation grouped by KAT7-low versus KAT7-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT7→partner) and Y-score (partner→KAT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of hematopoietic stem cell proliferation →	+0.175	+0.686	<.001	<.001	3	20
BONE	DNA replication-dependent chromatin disassembly →	+0.216	+0.735	<.001	<.001	3	20
KIDNEY	Regulation of DNA-templated DNA replication initiation →	+0.130	+0.720	<.001	.002	3	18
STOMACH	Epigenetic regulation of gene expression →	+0.085	+0.857	<.001	.002	3	17
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.115	+0.533	<.001	.003	3	16
STOMACH	Negative regulation of gene expression, epigenetic →	+0.091	+0.767	.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,438 associations by consensus.

Positive regulation of hematopoietic stem cell proliferation by KAT7 expression — LUNG_SCLC

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