KAT7

Across TCGA cell cohorts, KAT7 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KAT7-associated genes across cancer lineages are OR10A7, RBMY1E, and SI. Each is linked with KAT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KAT7-to-partner and partner-to-KAT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A7 grouped by KAT7-low versus KAT7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT7→partner) and Y-score (partner→KAT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10A7 →	+0.023	+6.022	<.001	.001	3	1
SKIN	RBMY1E →	+0.262	+4.977	<.001	.007	3	1
SKIN	SI →	+0.006	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	AGXT2 →	+0.014	+3.786	<.001	.001	3	1
LUNG_NSCLC_LUAD	IGSF21 →	+0.832	+4.082	<.001	.001	3	1
LUNG_NSCLC_LUAD	PRLHR →	+0.036	+3.362	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR10A7 by KAT7 expression — SKIN

Explore this box plot interactively →