KAT6A

Across TCGA patient cohorts, KAT6A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,224 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KAT6A-associated proteins across cancer lineages are POLB, NSD3, and IKBKB. Each is linked with KAT6A in more than 7 cancer types. Because this analysis shows association rather than direction, both KAT6A-to-partner and partner-to-KAT6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT6A versus POLB in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT6A→partner) and Y-score (partner→KAT6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLB →	+0.500	+0.579	<.001	<.001	3	8
LSCC	NSD3 →	+0.563	+0.559	<.001	<.001	3	7
BRCA	IKBKB →	+0.338	+0.631	<.001	<.001	3	5
LSCC	AP3M2 →	+0.310	+0.636	<.001	<.001	3	5
GBM	BRD3 →	+0.345	+0.291	<.001	<.001	3	5
PDAC	DPY30 →	+0.506	+0.440	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,224 associations by consensus.

KAT6A vs POLB — LSCC

Explore this scatter interactively →