KAT6A

Across TCGA patient cohorts, KAT6A protein abundance is significantly associated with the RNA expression of many other genes, with 4,530 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KAT6A-associated genes across cancer lineages are GPAT4, CCDC150, and GOLGA7. Each is linked with KAT6A in more than 3 cancer types. Because this analysis shows association rather than direction, both KAT6A-to-partner and partner-to-KAT6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT6A versus GPAT4 in BRCA, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT6A→partner) and Y-score (partner→KAT6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GPAT4 →	+0.590	+0.326	<.001	<.001	3	4
PDAC	CCDC150 →	+0.615	+0.377	.003	.005	2	4
BRCA	GOLGA7 →	+0.708	+0.542	<.001	<.001	3	3
OV	FNTA →	+0.625	+0.491	.003	.005	3	3
OV	AP3M2 →	+0.750	+0.528	.004	.007	3	3
OV	VDAC3 →	+0.576	+0.375	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,530 associations by consensus.

KAT6A vs GPAT4 — BRCA

Explore this scatter interactively →