KAT2B

Across TCGA patient cohorts, KAT2B protein abundance is significantly associated with the RNA expression of many other genes, with 15,070 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KAT2B-associated genes across cancer lineages are GINS1, MCM4, and FBXO5. Each is linked with KAT2B in more than 2 cancer types. Because this analysis shows association rather than direction, both KAT2B-to-partner and partner-to-KAT2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT2B versus GINS1 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT2B→partner) and Y-score (partner→KAT2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GINS1 →	-0.755	-0.309	.002	.009	3	3
BRCA	MCM4 →	-0.805	-0.371	.001	.001	3	3
BRCA	FBXO5 →	-1.029	-0.493	.001	.001	3	3
BRCA	KIF14 →	-0.989	-0.335	<.001	.004	3	3
OV	NDUFAF4 →	-0.806	-1.112	<.001	.002	3	3
BRCA	SLC5A6 →	-1.176	-0.465	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,070 associations by consensus.

KAT2B vs GINS1 — BRCA

Explore this scatter interactively →