KAT2B

Across TCGA cell cohorts, KAT2B mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KAT2B-associated genes across cancer lineages are IL17F, OR52N4, and CLLU1-AS1. Each is linked with KAT2B in more than 1 cancer types. Because this analysis shows association rather than direction, both KAT2B-to-partner and partner-to-KAT2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL17F grouped by KAT2B-low versus KAT2B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT2B→partner) and Y-score (partner→KAT2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL17F →	+0.070	+3.855	<.001	.007	3	2
URINARY_TRACT	OR52N4 →	+0.023	+5.087	<.001	.004	3	1
URINARY_TRACT	CLLU1-AS1 →	+0.113	+5.087	<.001	.004	3	1
URINARY_TRACT	OR10G4 →	+0.016	+5.087	<.001	.004	3	1
URINARY_TRACT	CFAP97D2 →	+0.043	+5.087	<.001	.004	3	1
SKIN	TINAG →	+0.207	+3.678	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

IL17F by KAT2B expression — BLOOD_Leukemia

Explore this box plot interactively →