KAT2A

Across TCGA cell cohorts, KAT2A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,168 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KAT2A-associated GO terms across cancer lineages are Chiasma assembly, Telomere maintenance, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with KAT2A in more than 16 cancer types. Because this analysis shows association rather than direction, both KAT2A-to-partner and partner-to-KAT2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chiasma assembly grouped by KAT2A-low versus KAT2A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT2A→partner) and Y-score (partner→KAT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Chiasma assembly →	+0.270	+0.967	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Telomere maintenance →	+0.072	+1.076	.007	.002	3	15
OESOPHAGUS	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.124	+0.916	.002	<.001	3	14
BONE	Mitochondrial DNA metabolic process →	+0.099	+0.786	<.001	<.001	3	14
BONE	Telomere organization →	+0.093	+1.147	.005	.003	3	14
URINARY_TRACT	IMP biosynthetic process →	+0.172	+0.738	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,168 associations by consensus.

Chiasma assembly by KAT2A expression — KIDNEY

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