KAT14

Across TCGA patient cohorts, KAT14 protein abundance is significantly associated with the RNA expression of many other genes, with 9,154 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KAT14-associated genes across cancer lineages are CCDC134, MCAT, and NELFCD. Each is linked with KAT14 in more than 2 cancer types. Because this analysis shows association rather than direction, both KAT14-to-partner and partner-to-KAT14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT14 versus CCDC134 in LSCC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT14→partner) and Y-score (partner→KAT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCDC134 →	+0.422	+0.286	<.001	<.001	3	3
LSCC	MCAT →	+0.417	+0.257	<.001	<.001	3	3
LSCC	NELFCD →	+0.549	+0.299	.001	<.001	3	3
LSCC	SRSF11 →	+0.354	+0.259	.002	.001	3	3
LSCC	WARS2 →	+0.550	+0.347	.002	<.001	3	3
LUAD	VAPB →	+0.387	+0.282	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,154 associations by consensus.

KAT14 vs CCDC134 — LSCC

Explore this scatter interactively →