KAT14

Across TCGA cell cohorts, KAT14 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KAT14-associated genes across cancer lineages are CD1B, F13B, and SIX6. Each is linked with KAT14 in more than 1 cancer types. Because this analysis shows association rather than direction, both KAT14-to-partner and partner-to-KAT14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD1B grouped by KAT14-low versus KAT14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT14→partner) and Y-score (partner→KAT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CD1B →	+2.865	+3.619	.002	.007	3	2
OESOPHAGUS	F13B →	+0.054	+3.977	<.001	.006	3	1
OESOPHAGUS	SIX6 →	+0.006	+3.836	<.001	.004	3	1
OESOPHAGUS	OR8A1 →	+0.142	+3.836	<.001	.004	3	1
OESOPHAGUS	OR10D3 →	+0.166	+3.836	<.001	.004	3	1
OESOPHAGUS	OR8G1 →	+0.052	+3.836	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

CD1B by KAT14 expression — BLOOD_Leukemia

Explore this box plot interactively →