KASH5

Across TCGA patient cohorts, KASH5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,051 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KASH5-associated GO terms across cancer lineages are Ribosomal large subunit biogenesis, RNA modification, and Positive regulation of cell cycle G2/M phase transition. Each is linked with KASH5 in more than 19 cancer types. Because this analysis shows association rather than direction, both KASH5-to-partner and partner-to-KASH5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit biogenesis grouped by KASH5-low versus KASH5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KASH5→partner) and Y-score (partner→KASH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribosomal large subunit biogenesis →	+0.067	+0.147	<.001	<.001	3	20
STAD	RNA modification →	+0.060	+0.132	<.001	<.001	3	18
ESCA	Positive regulation of cell cycle G2/M phase transition →	+0.074	+0.206	<.001	<.001	3	18
STAD	Microtubule cytoskeleton organization involved in mitosis →	+0.074	+0.173	<.001	<.001	3	18
STAD	Regulation of DNA repair →	+0.060	+0.171	<.001	<.001	3	18
ESCA	Negative regulation of DNA-templated transcription, elongation →	+0.068	+0.144	<.001	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,051 associations by consensus.

Ribosomal large subunit biogenesis by KASH5 expression — STAD

Explore this box plot interactively →