KANSL1L-AS1

Across TCGA pan-cancer cohorts, KANSL1L-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KANSL1L-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KANSL1L-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types KANSL1L-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, LIHC, and THCA are the cancer types where KANSL1L-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KANSL1L-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.681	<.001	9	view →
LIHC	All	All	+0.173	<.001	8	view →
THCA	Female	II,III,IV	−0.633	<.001	7	view →
BRCA	All	III,IV	−0.499	<.001	6	view →
KIRC	Female	All	+0.345	<.001	6	view →
COAD	All	All	+0.286	<.001	6	view →
STAD	Male	II,III,IV	+0.384	.016	4	view →
CHOL	All	All	+1.142	<.001	3	view →
KIRP	All	IV	+0.684	.005	2	view →
READ	Female	All	+0.680	.003	2	view →
LUSC	Male	III,IV	−0.550	.048	1	view →
HNSC	All	III,IV	+0.098	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KANSL1L-AS1–KICH

Open the KICH breakdown →