KANSL1

Across TCGA pan-cancer cohorts, KANSL1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated KANSL1 data layer compared with 20 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KANSL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KANSL1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where KANSL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.834	0.578	.009	15	view →
HNSC	DFS	Quartile	IV	1.000	0.518	.001	14	view →
PDAC	DFS	Median	All	0.361	0.213	.034	10	view →
LSCC	OS	Quartile	II,III,IV	1.000	0.772	.019	5	view →
UCEC	DFS	Median	II,III,IV	0.550	0.848	.038	4	view →
LUAD	OS	Median	II,III,IV	0.863	0.999	.039	3	view →
GBM	DFS	Quartile	All	0.847	0.563	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

KANSL1–CCRCC (DFS)

Open the CCRCC breakdown →