KANSL1

Across TCGA cell cohorts, KANSL1 mutation is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KANSL1-associated genes across cancer lineages are CBLIF, TFDP3, and FBXO40. Each is linked with KANSL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KANSL1-to-partner and partner-to-KANSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBLIF grouped by KANSL1-low versus KANSL1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL1→partner) and Y-score (partner→KANSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CBLIF →	+0.033	+4.115	.001	.001	3	2
SOFT_TISSUE	TFDP3 →	+0.780	+4.169	<.001	.002	3	2
LARGE_INTESTINE	FBXO40 →	+0.003	+2.204	<.001	.005	3	2
LARGE_INTESTINE	CATSPER4 →	+0.059	+2.366	<.001	.003	3	2
LARGE_INTESTINE	NOP14 →	+0.641	+2.502	<.001	.005	3	2
LARGE_INTESTINE	F11 →	+0.035	+2.660	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

CBLIF by KANSL1 expression — OESOPHAGUS

Explore this box plot interactively →