KANK4

Across TCGA cell cohorts, KANK4 mutation is significantly associated with the RNA expression of many other genes, with 173 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KANK4-associated genes across cancer lineages are IFNA8, PTH2, and TCP10L2. Each is linked with KANK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KANK4-to-partner and partner-to-KANK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA8 grouped by KANK4-low versus KANK4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANK4→partner) and Y-score (partner→KANK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA8 →	+0.052	+4.930	<.001	.008	3	2
LUNG_NSCLC_LUAD	PTH2 →	+0.131	+3.218	<.001	.001	3	2
SKIN	TCP10L2 →	+0.048	+3.192	.002	.002	3	2
BLOOD_Leukemia	ASZ1 →	+0.230	+4.567	<.001	.001	3	2
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR2W1 →	+0.023	+5.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 173 associations by consensus.

IFNA8 by KANK4 expression — SOFT_TISSUE

Explore this box plot interactively →