Across TCGA patient cohorts, KANK2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,108 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KANK2-associated genes across cancer lineages are MYL9, SRPX, and ASPN. Each is linked with KANK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both KANK2-to-partner and partner-to-KANK2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANK2→partner) and Y-score (partner→KANK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.424	+0.703	<.001	<.001	3	10
BRCA	SRPX →	+1.436	+0.566	<.001	<.001	3	10
BRCA	ASPN →	+2.119	+0.640	<.001	<.001	3	10
BRCA	PMP22 →	+0.976	+0.553	<.001	<.001	3	10
OV	C7 →	+2.894	+0.403	<.001	<.001	3	10
UCEC	EFEMP1 →	+1.405	+0.811	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,108 associations by consensus.

Exploration

KANK2 survival (RNA) · tumor vs normal (RNA) · all KANK2 data types