Across TCGA cell cohorts, KANK2 mutation is significantly associated with the RNA expression of many other genes, with 79 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KANK2-associated genes across cancer lineages are C8orf74, OR4X2, and C10orf53. Each is linked with KANK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KANK2-to-partner and partner-to-KANK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANK2→partner) and Y-score (partner→KANK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C8orf74 →	+0.022	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR4X2 →	+0.024	+4.369	<.001	.008	3	1
SOFT_TISSUE	C10orf53 →	+0.009	+4.369	<.001	.008	3	1
CNS	PRM3 →	+0.178	+5.754	<.001	.002	3	1
SKIN	GJA10 →	+0.018	+3.345	<.001	.001	3	1
SKIN	OR3A3 →	+0.128	+2.688	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

Exploration

KANK2 survival (RNA) · tumor vs normal (RNA) · all KANK2 data types