KANK1

Across TCGA cell cohorts, KANK1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,872 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KANK1-associated genes across cancer lineages are DOCK8, CLN6, and RAB11FIP4. Each is linked with KANK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both KANK1-to-partner and partner-to-KANK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KANK1 versus DOCK8 in URINARY_TRACT, with a Pearson correlation of 0.50.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANK1→partner) and Y-score (partner→KANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DOCK8 →	+1.859	+1.008	.001	.005	1	8
SKIN	CLN6 →	+1.014	+1.467	<.001	<.001	3	5
LIVER	RAB11FIP4 →	+2.818	+1.800	<.001	<.001	3	5
OVARY	SLC12A9 →	+0.873	+1.446	<.001	<.001	3	5
BREAST	EYA3 →	+0.828	+1.929	<.001	<.001	3	5
BLOOD_Lymphoma	MLXIP →	+1.234	+2.051	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,872 associations by consensus.

KANK1 vs DOCK8 — URINARY_TRACT

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