KAAG1

Across TCGA patient cohorts, KAAG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,103 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KAAG1-associated GO terms across cancer lineages are Mitochondrial gene expression, Amino acid activation, and tRNA aminoacylation for mitochondrial protein translation. Each is linked with KAAG1 in more than 15 cancer types. Because this analysis shows association rather than direction, both KAAG1-to-partner and partner-to-KAAG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by KAAG1-low versus KAAG1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KAAG1→partner) and Y-score (partner→KAAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial gene expression →	+0.071	+0.276	<.001	<.001	3	16
STAD	Amino acid activation →	+0.051	+0.189	<.001	<.001	3	14
ESCA	tRNA aminoacylation for mitochondrial protein translation →	+0.056	+0.256	<.001	<.001	3	14
STAD	Macromolecule methylation →	+0.050	+0.182	<.001	<.001	3	14
STAD	Positive regulation of chromosome organization →	+0.058	+0.176	<.001	<.001	3	13
STAD	Regulation of mitochondrial membrane permeability →	+0.058	+0.163	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,103 associations by consensus.

Mitochondrial gene expression by KAAG1 expression — ESCA

Explore this box plot interactively →