KAAG1

Across TCGA cell cohorts, KAAG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,605 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KAAG1-associated GO terms across cancer lineages are Negative regulation of chondrocyte differentiation, Regulation of angiotensin-activated signaling pathway, and Tie signaling pathway. Each is linked with KAAG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KAAG1-to-partner and partner-to-KAAG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chondrocyte differentiation grouped by KAAG1-low versus KAAG1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KAAG1→partner) and Y-score (partner→KAAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of chondrocyte differentiation →	-0.213	-1.022	<.001	<.001	3	6
BONE	Regulation of angiotensin-activated signaling pathway →	-0.223	-1.275	<.001	<.001	3	5
BONE	Tie signaling pathway →	-1.450	-1.068	<.001	<.001	3	5
KIDNEY	Negative regulation of chondrocyte development →	-0.962	-0.974	.003	.002	2	6
BONE	Negative regulation of cartilage development →	-0.224	-1.407	<.001	<.001	3	5
SKIN	Transepithelial water transport →	-0.831	-0.145	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,605 associations by consensus.

Negative regulation of chondrocyte differentiation by KAAG1 expression — BONE

Explore this box plot interactively →