JUP

Across TCGA patient cohorts, JUP RNA expression is significantly associated with the protein abundance of many other proteins, with 15,997 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JUP-associated proteins across cancer lineages are JUP_S665, NGLY1, and CD74. Each is linked with JUP in more than 5 cancer types. Because this analysis shows association rather than direction, both JUP-to-partner and partner-to-JUP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JUP versus JUP_S665 in HNSC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JUP→partner) and Y-score (partner→JUP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	JUP_S665 →	+0.926	+0.723	<.001	<.001	3	6
UCEC	NGLY1 →	-0.252	-0.677	<.001	.006	3	5
HNSC	CD74 →	-0.677	-0.690	<.001	.001	3	5
HNSC	TNS3 →	-0.402	-1.064	<.001	<.001	3	5
HNSC	NBAS →	-0.152	-1.057	.001	<.001	3	4
HNSC	ZNF185 →	+0.846	+0.816	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,997 associations by consensus.

JUP vs JUP_S665 — HNSC

Explore this scatter interactively →