JTB

Across TCGA patient cohorts, JTB RNA expression is significantly associated with the protein abundance of many other proteins, with 11,830 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JTB-associated proteins across cancer lineages are DUSP12, UBE2Q1, and PRUNE1. Each is linked with JTB in more than 5 cancer types. Because this analysis shows association rather than direction, both JTB-to-partner and partner-to-JTB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JTB versus DUSP12 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JTB→partner) and Y-score (partner→JTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DUSP12 →	+0.274	+0.355	<.001	.001	3	6
UCEC	UBE2Q1 →	+0.355	+1.148	<.001	<.001	3	6
LUAD	PRUNE1 →	+0.378	+0.505	<.001	<.001	3	6
LSCC	UBAP2L →	+0.224	+0.403	<.001	<.001	3	6
LSCC	PRCC →	+0.299	+0.467	<.001	<.001	3	6
BRCA	RPRD2 →	+0.373	+0.553	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,830 associations by consensus.

JTB vs DUSP12 — BRCA

Explore this scatter interactively →