JTB

Across TCGA cell cohorts, JTB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,835 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible JTB-associated GO terms across cancer lineages are Flavin-containing compound metabolic process, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Protein targeting to Golgi apparatus. Each is linked with JTB in more than 10 cancer types. Because this analysis shows association rather than direction, both JTB-to-partner and partner-to-JTB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flavin-containing compound metabolic process grouped by JTB-low versus JTB-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JTB→partner) and Y-score (partner→JTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Flavin-containing compound metabolic process →	+0.199	+0.689	.003	.003	2	11
BREAST	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.228	+0.925	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Protein targeting to Golgi apparatus →	+0.208	+1.206	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Malate transport →	+0.174	+0.837	<.001	.007	3	9
LUNG_NSCLC_LUAD	Malate transmembrane transport →	+0.174	+0.837	<.001	.007	3	9
LIVER	Cell junction disassembly →	-0.181	-0.717	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,835 associations by consensus.

Flavin-containing compound metabolic process by JTB expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →