Across TCGA patient cohorts, JRKL mutation is significantly associated with the RNA expression of many other genes, with 5,835 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JRKL-associated genes across cancer lineages are RNA5SP411, OR10H3, and OR7E97P. Each is linked with JRKL in more than 2 cancer types. Because this analysis shows association rather than direction, both JRKL-to-partner and partner-to-JRKL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JRKL→partner) and Y-score (partner→JRKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.763	+1.677	<.001	<.001	3	3
BLCA	OR10H3 →	+0.041	+6.048	<.001	<.001	3	3
BLCA	OR7E97P →	+0.042	+4.704	<.001	.005	3	3
LUSC	KRTAP20-3 →	+0.839	+7.924	<.001	.008	3	3
UCEC	LINC02084 →	+0.363	+2.169	<.001	<.001	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,835 associations by consensus.

Exploration

JRKL survival (RNA) · tumor vs normal (RNA) · all JRKL data types