Across TCGA cell cohorts, JRKL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,258 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible JRKL-associated GO terms across cancer lineages are Positive regulation of protein K48-linked ubiquitination, Negative regulation of protein export from nucleus, and Maintenance of location. Each is linked with JRKL in more than 12 cancer types. Because this analysis shows association rather than direction, both JRKL-to-partner and partner-to-JRKL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JRKL→partner) and Y-score (partner→JRKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of protein K48-linked ubiquitination →	+0.151	+0.675	<.001	.002	3	13
URINARY_TRACT	Negative regulation of protein export from nucleus →	+0.115	+0.633	<.001	.004	3	12
SOFT_TISSUE	Maintenance of location →	+0.091	+0.779	<.001	<.001	3	12
OVARY	Maintenance of location in cell →	+0.097	+0.867	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.129	+1.078	<.001	<.001	3	11
OVARY	Positive regulation of protein polyubiquitination →	+0.117	+0.784	.004	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,258 associations by consensus.

Exploration

JRKL survival (RNA) · tumor vs normal (RNA) · all JRKL data types