JRKL-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, JRKL-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated JRKL-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher JRKL-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated JRKL-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SARC show a favorable association.

LUAD, BLCA, and BRCA are the cancer types where JRKL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileIV0.3430.778.00142view →
BLCADFSTertileAll0.8130.418.00136view →
BRCADFSTertileIII,IV0.6740.807.01433view →
HNSCOSTertileIV0.2820.536.02327view →
KIRPOSTertileII,III,IV0.6070.879.01224view →
UVMOSTertileAll0.2920.674.03518view →
CHOLOSTertileIII,IV0.2750.886.04518view →
CESCOSTertileAll0.6540.811.02118view →
LGGDFSTertileAll0.6420.754.02812view →
COADDFSTertileIV0.2110.509.0079view →
SARCOSTertileAll1.0000.703.0219view →
ACCDFSTertileIII,IV0.0570.457.0409view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

JRKL-AS1–LUAD (DFS)

Kaplan–Meier survival curve for JRKL-AS1 RNA-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration