JPT2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, JPT2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated JPT2 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher JPT2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated JPT2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, GBM, and HNSC are the cancer types where JPT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianIII,IV1.0000.274.00238view →
GBMDFSTertileAll0.2940.553.00220view →
HNSCDFSTertileAll0.3220.947.01418view →
CCRCCDFSQuartileAll0.5420.878.00910view →
LSCCDFSQuartileAll0.8550.520.0213view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration