Across TCGA patient cohorts, JPT1 mutation is significantly associated with the RNA expression of many other genes, with 1,155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JPT1-associated genes across cancer lineages are SDR42E1P2, CWC25, and RNA5SP414. Each is linked with JPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both JPT1-to-partner and partner-to-JPT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPT1→partner) and Y-score (partner→JPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SDR42E1P2 →	+0.079	+8.055	<.001	.007	3	1
UCEC	CWC25 →	+0.462	+2.617	.005	.006	3	1
UCEC	RNA5SP414 →	+0.724	+2.840	<.001	<.001	3	1
UCEC	ZNF280B →	+0.634	+3.329	.001	.005	3	1
UCEC	RNA5SP411 →	+1.557	+2.808	<.001	<.001	3	1
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,155 associations by consensus.

Exploration

JPT1 survival (RNA) · tumor vs normal (RNA) · all JPT1 data types