Across TCGA patient cohorts, JPT1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JPT1-associated genes across cancer lineages are IGFBP2, MEK1, and Myosin-IIa_pS1943. Each is linked with JPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both JPT1-to-partner and partner-to-JPT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPT1→partner) and Y-score (partner→JPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.775	-2.321	.017	.035	3	1
UCEC	MEK1 →	+0.381	+2.321	.038	.035	3	1
UCEC	Myosin-IIa_pS1943 →	+0.243	+2.335	.019	.020	3	1
UCEC	p62 Lck ligand →	+0.402	+3.169	.014	.018	3	1
UCEC	Annexin-1 →	+0.605	+2.827	.022	.035	3	1
UCEC	AMPK_pT172 →	+0.446	+3.472	.030	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

JPT1 survival (RNA) · tumor vs normal (RNA) · all JPT1 data types