JPH3

Across TCGA patient cohorts, JPH3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,128 significant associations in total. GBM shows the largest number of these associations.

The most reproducible JPH3-associated genes across cancer lineages are LGALS1, SLC16A8, and SEPTIN3. Each is linked with JPH3 in more than 1 cancer types. Because this analysis shows association rather than direction, both JPH3-to-partner and partner-to-JPH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JPH3 versus LGALS1 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH3→partner) and Y-score (partner→JPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LGALS1 →	-0.724	-0.609	.001	.003	3	1
GBM	SLC16A8 →	+0.816	+0.562	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.433	+0.560	<.001	<.001	3	1
GBM	XBP1 →	-0.622	-0.542	.001	.002	3	1
GBM	RASL10A →	+0.912	+0.532	.002	.005	3	1
GBM	NEFH →	+1.249	+0.567	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,128 associations by consensus.

JPH3 vs LGALS1 — GBM

Explore this scatter interactively →