JPH3

Across TCGA cell cohorts, JPH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,142 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible JPH3-associated GO terms across cancer lineages are Heterochromatin formation, DNA-templated transcription initiation, and Positive regulation of DNA metabolic process. Each is linked with JPH3 in more than 9 cancer types. Because this analysis shows association rather than direction, both JPH3-to-partner and partner-to-JPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by JPH3-low versus JPH3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH3→partner) and Y-score (partner→JPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Heterochromatin formation →	+0.059	+1.445	<.001	.004	3	10
STOMACH	DNA-templated transcription initiation →	+0.073	+2.084	<.001	.002	3	10
BREAST	Positive regulation of DNA metabolic process →	+0.042	+0.886	<.001	<.001	3	10
STOMACH	UV-damage excision repair →	+0.080	+1.534	<.001	<.001	3	10
LUNG_NSCLC_LUSC	U2-type prespliceosome assembly →	+0.093	+1.852	<.001	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.079	+1.098	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,142 associations by consensus.

Heterochromatin formation by JPH3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →