JPH3

Across TCGA cell cohorts, JPH3 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. CNS shows the largest number of these associations.

The most reproducible JPH3-associated genes across cancer lineages are ZNF705G, SIX6, and GAGE10. Each is linked with JPH3 in more than 1 cancer types. Because this analysis shows association rather than direction, both JPH3-to-partner and partner-to-JPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF705G grouped by JPH3-low versus JPH3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH3→partner) and Y-score (partner→JPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ZNF705G →	+0.032	+4.467	<.001	.004	3	2
BLOOD_Myeloma	SIX6 →	+0.007	+4.285	<.001	.003	3	1
BLOOD_Myeloma	GAGE10 →	+0.153	+3.906	<.001	.009	3	1
LUNG_NSCLC_LUSC	MAGEB3 →	+0.051	+4.108	<.001	.005	3	1
LARGE_INTESTINE	OCM2 →	+0.047	+3.700	<.001	.009	3	1
LARGE_INTESTINE	MMP26 →	+0.027	+3.217	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

ZNF705G by JPH3 expression — SKIN

Explore this box plot interactively →