JPH3

Across TCGA cell cohorts, JPH3 mutation is significantly associated with the mutation status of many other genes, with 2,365 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible JPH3-associated genes across cancer lineages are BAZ2A, PCDH9, and SGO2. Each is linked with JPH3 in more than 5 cancer types. Because this analysis shows association rather than direction, both JPH3-to-partner and partner-to-JPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BAZ2A grouped by JPH3-low versus JPH3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH3→partner) and Y-score (partner→JPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	BAZ2A →	+3.316	+3.906	.004	.004	1	6
UPPER_AERODIGESTIVE_TRACT	PCDH9 →	+5.392	+5.392	.004	.004	1	5
LUNG_NSCLC_LUAD	SGO2 →	+4.772	+5.339	.004	.004	1	5
CNS	GRIK2 →	+5.614	+5.044	.003	.003	1	5
STOMACH	TIAM1 →	+3.357	+4.285	.005	.005	1	5
STOMACH	PTPRT →	+3.357	+4.285	.005	.005	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,365 associations by consensus.

BAZ2A by JPH3 expression — SKIN

Explore this box plot interactively →