JPH2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JPH2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,483 significant associations in total. GBM shows the largest number of these associations.

The most reproducible JPH2-associated genes across cancer lineages are GLT8D2, MFAP5, and ACTA2. Each is linked with JPH2 in more than 8 cancer types. Because this analysis shows association rather than direction, both JPH2-to-partner and partner-to-JPH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JPH2 versus GLT8D2 in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH2→partner) and Y-score (partner→JPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGLT8D2 →+1.934+0.807<.001<.00139
OVMFAP5 →+1.895+0.629.001.00139
OVACTA2 →+1.526+0.616<.001<.00138
OVPMP22 →+1.282+0.803<.001<.00138
COADCNN1 →+2.086+0.736<.001<.00138
OVTPM1 →+1.342+0.822<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,483 associations by consensus.

JPH2 vs GLT8D2 — OV

Per-sample scatter of JPH2 vs GLT8D2 in OV (Pearson r = 0.52).

Explore this scatter interactively →

Exploration