JPH1

Across TCGA cell cohorts, JPH1 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible JPH1-associated genes across cancer lineages are TNMD, GPX6, and RP1. Each is linked with JPH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both JPH1-to-partner and partner-to-JPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNMD grouped by JPH1-low versus JPH1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH1→partner) and Y-score (partner→JPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TNMD →	+0.010	+4.247	<.001	.004	3	2
SOFT_TISSUE	GPX6 →	+0.023	+5.369	<.001	.004	3	1
BLOOD_Leukemia	RP1 →	+0.054	+3.474	.001	.007	3	1
BLOOD_Leukemia	RERGL →	+0.872	+3.017	<.001	.007	3	1
BLOOD_Leukemia	OR11H1 →	+0.058	+3.786	<.001	.002	3	1
BLOOD_Leukemia	SH3GL3 →	+1.843	+3.518	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

TNMD by JPH1 expression — BLOOD_Lymphoma

Explore this box plot interactively →