JMY

Across TCGA cell cohorts, JMY mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible JMY-associated genes across cancer lineages are CRYBB3, HHLA1, and MCHR2. Each is linked with JMY in more than 1 cancer types. Because this analysis shows association rather than direction, both JMY-to-partner and partner-to-JMY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB3 grouped by JMY-low versus JMY-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMY→partner) and Y-score (partner→JMY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CRYBB3 →	+0.075	+4.152	.004	.009	3	1
BLOOD_Leukemia	HHLA1 →	+0.006	+4.551	.002	.004	3	1
BLOOD_Leukemia	MCHR2 →	+0.034	+4.539	<.001	.007	3	1
BLOOD_Leukemia	BSND →	+0.018	+4.551	<.001	.004	3	1
BLOOD_Leukemia	KNCN →	+0.048	+4.276	<.001	.007	3	1
BLOOD_Leukemia	OR9K2 →	+0.021	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

CRYBB3 by JMY expression — BLOOD_Leukemia

Explore this box plot interactively →