JMJD6

Across TCGA patient cohorts, JMJD6 RNA expression is significantly associated with the mutation status of many other genes, with 13,115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JMJD6-associated genes across cancer lineages are TP53, OBSCN, and GTF3C1. Each is linked with JMJD6 in more than 8 cancer types. Because this analysis shows association rather than direction, both JMJD6-to-partner and partner-to-JMJD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by JMJD6-low versus JMJD6-high in SARC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD6→partner) and Y-score (partner→JMJD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	TP53 →	+1.584	+0.269	<.001	<.001	3	9
UCEC	OBSCN →	+1.036	+0.346	<.001	<.001	3	5
UCEC	GTF3C1 →	+1.854	+0.411	<.001	<.001	3	5
HNSC	PCDH15 →	+1.916	+0.248	.003	.003	3	4
LUAD	TTN →	+0.864	+0.142	<.001	.001	3	4
LUAD	CSMD3 →	+1.150	+0.212	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,115 associations by consensus.

TP53 by JMJD6 expression — SARC

Explore this box plot interactively →